What should patients on tricyclic antidepressants avoid due to potential side effects?

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Patients taking tricyclic antidepressants should avoid alcohol due to the potential for adverse effects. Alcohol can enhance the sedative properties of these medications, leading to increased drowsiness, dizziness, and impairment. Additionally, alcohol can exacerbate the symptoms of depression and anxiety, counteracting the benefits of the antidepressant treatment.

While it is important for patients to consider interactions with over-the-counter and prescription medications, the emphasis on avoiding alcohol is particularly significant given its immediate impact on CNS (central nervous system) function and the overall risk of complications. Engaging in physical activity is typically not contraindicated, as it can have positive effects on mental health and overall well-being. Therefore, the recommendation for patients on tricyclic antidepressants is to refrain from consuming alcohol to maintain their safety and the efficacy of their treatment.

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